Life Science Optics
System Solutions — Case Study
Next-Generation Fluorescence-Based Life Science Instrument
The diagram below showcases a prototype developed for a next-generation fluorescence-based life science instrument
Multi-Wavelength LED & Laser Based Light Engine
- High brightness multi-color illumination in a compact and fully integrated design
- Customized beam shaping with highly uniform flat-top profile, speckle reducer
- Outstanding reliability and power stability
Optimized Fluorescence Imaging
- High-performance Semrock brand filters enable multi-color imaging with best sensitivity and spectral purity
- Custom sizing, shaping edge blackening to fit any instrument design and performance requirement
Electromechanical Integration
- Established partnerships with industry leaders for motion control, sensors, cameras, and in-house capability for control electronics
- Developed high precision laser autofocus system with fast piezo stage to compensate for flow cell variations
- Designed to image on next-gen large format camera
Full Product Qualification
- Full control over the entire system with extensive end-to-end simulation and design validation
- Wavefront characterization of the complete system at the operating wavelengths
- Dedicated test station to measure “as-used” imaging quality and autofocus performance
- Environmental and product reliability testing
Optomechanical Integration
- Design-for-manufacturability with precision integrated system alignment
- Robust and innovative adjustment mechanisms
- Low-stress and ultra-stable optical mounts
- Control of stray light, thermal sensitivity, resonant frequencies and mechanical stress
- Upgradeability and compact footprint
Custom Objective Solution with Imaging Tube Lens
- High-NA wide-FOV with diffraction limited resolution
- Guaranteed performances over the entire FOV and all spectral bands, including extra low distortion and minimized variability between channels
- Superior unit-to-unit repeatability
