Case Study - IDEX Health & ScienceIDEX Health & Science

    System Solutions — Case Study

    Next-Generation Fluorescence-Based Life Science Instrument

    The diagram below showcases a prototype developed for a next-generation fluorescence-based life science instrument.

    Multi-Wavelength LED & Laser Based Light Engine

    • High brightness multi-color illumination in a compact and fully integrated design
    • Customized beam shaping with highly uniform flat-top profile, speckle reducer
    • Outstanding reliability and power stability

    Optimized Fluorescence Imaging

    • High-performance Semrock brand filters enable multi-color imaging with best sensitivity and spectral purity
    • Custom sizing, shaping edge blackening to fit any instrument design and performance requirement

    Electromechanical Integration

    • Established partnerships with industry leaders for motion control, sensors, cameras, and in-house capability for control electronics
    • Developed high precision laser autofocus system with fast piezo stage to compensate for flow cell variations
    • Designed to image on next-gen large format camera

    Full Product Qualification

    • Full control over the entire system with extensive end-to-end simulation and design validation
    • Wavefront characterization of the complete system at the operating wavelengths
    • Dedicated test station to measure “as-used” imaging quality and autofocus performance
    • Environmental and product reliability testing

    Optomechanical Integration

    • Design-for-manufacturability with precision integrated system alignment
    • Robust and innovative adjustment mechanisms
    • Low-stress and ultra-stable optical mounts
    • Control of stray light, thermal sensitivity, resonant frequencies and mechanical stress
    • Upgradeability and compact footprint

    Custom Objective Solution with Imaging Tube Lens

    • High-NA wide-FOV with diffraction limited resolution
    • Guaranteed performances over the entire FOV and all spectral bands, including extra low distortion and minimized variability between channels
    • Superior unit-to-unit repeatability


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    IDEX Health & Science is the global authority in fluidics and optics, bringing to life advanced optofluidic technologies with our products, people, and engineering expertise. Intelligent solutions for life.