Equipment manufacturers in the Biopharmaceutical fluidics space often struggle to find a simple workflow for characterizing biotherapeutic molecules and their production processes. Lack of real-time CQA/CPP data from cell culture process is a pain point that adds time and complexity to biotherapeutic drug development. This presents a massive challenge to the commercialization of the growing number of promising therapies in the development pipeline.
IDEX Health & Science is bridging the gap between the cell culture process and analytical instrumentation at all scales; from R&D to manufacturing. We partner with life science instrument manufacturers to develop innovative, consistent, and easy to integrate solutions for challenging analytical workflows in biopharma. From sample prep to detection, we have application expertise in chromatography, bioprocessing PAT, and related fluidics. How do you envision your analytical platform being deployed in a seamlessly integrated PAT environment? Partner with IDEX Health & Science to make your vision a reality and accelerate biopharmaceutical development together.
Calibration can be one of the most tedious steps in any analytical workflow. IDEX Health & Science can create integration-ready solutions to automate calibration for mAb titer workflows.
Simple fluidic subsystem for automated Protein A calibration
Cell culture media analysis using CE-MS or LC-MS provides critical insight into cell health and productivity. IDEX Health & Science can create a pipette-free alternative to time-consuming manual precipitation dilution typically required for these methods.
Inline sample prep subsystem for cell culture media analysis
IDEX Health & Science can create custom subsystems to combine UV titer with intact mass analysis for a unified workflow. This is accomplished by an integrated buffer exchange procedure to prepare a sample for ionization in a mass spectrometer source.
Buffer exchange for unified mAb titer and intact mass
IDEX Health & Science can automate pipette-free, inline mAb sample prep for key workflows such as glycan analysis, peptide mapping, and multi-attribute methods (MAM). Our custom solutions can be tailored to any commercially available reagent kit including magnetic bead chemistry.
Inline solutions as a hands-free alternative to tedious pipette-based mAb sample prep workflows
The analytical challenges of biological drug development are immense, but we can streamline your workflows, improve performance, provide consistency, and accelerate your time to market.