Utilize degassing in your fluidic path to remove dissolved gases from fluids before they outgas and form problem-causing bubbles.
Full story
When designing integrated microfluidic consumables, it is important to understand the assay workflow, the functionality of the consumable, and how to scale the consumable for the markets you are looking to penetrate. All aspects of microfluidic consumable design can be carefully reviewed and strategically implemented with what we call an Assay and Reagent Plan.
Full story
Life Science instrument designers face many challenges when incorporating a fluid delivery system into an instrument. Many instruments on the market use a single positive displacement dispense pump because they are compact and easy to integrate. These systems force designers to make multiple compromises because pump displacement volume, pressure handling, flow rate, and flow duration are all interrelated. How can you achieve accurate, stable flow rates with unlimited flow in your liquid chromatography and mass spectrometry instruments?
Full story
Every time a traditional UHPLC valve is rotated to make an injection in a UHPLC system, the pressure of the mobile phase flowing through the column fluctuates. When switching from load to inject, the system experiences a 11,000 psi (758 bar, 76 MPa) pressure drop. In addition to the injection pressure drop, the column also experiences a pressure drop when the valve switches back to the load position from the inject position. Over time when switching the valve repeatedly, these pressure drops can disrupt column packing and cause the column to experience an early lifetime failure.
Full story
During reagent handling or at the connection junctions, even small changes in the fluid path can cause dissolved gasses to occur in a solution. Factors including pressure, temperature, and chemical mixing are sources of bubble formation. Bubbles in the fluid stream cause detection variables, which can produce unstable, wandering, or noisy baselines. How do you prevent these variable changes in your fluid path? A Degasser
Full story
The healthcare provider experience is constantly evolving as new diagnostic technologies are released that can provide more timely health status information at the point-of-care. What enables this technology to advance? The answer is Microfluidics.
Full story