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High-pressure mixing refers to a pumping system that involves multiple pumps. Here, each pump in the system delivers a specified amount of a solvent in the form of a solvent stream. All the solvent streams in a system then come together in a mixing apparatus before exiting as a unified solvent stream. It is referred to as high-pressure mixing because the solvent streams are mixed together after they leave the pump, thus being on the high-pressure side of the pump. This term usually applies to gradient methods, but may also apply to more sophisticated isocratic analyses.