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PFA tubing serves as an excellent replacement for PTFE Teflon, particularly where you are looking for similar physical properties—including lubricity—as those of PTFE, and where gas permeability, surface texture, and inertness are issues.
Additionally, a high-purity grade of PFA tubing is typically used when only the lowest level of polymer contaminants can be tolerated. This ultra-clean grade of PFA is often used in the medical industry.