Stories & Features

HPLC Column Hardware Components and Accessories

Sep 3, 2025 by IDEX Health & Science

Did you know that all of our Column Systems are available for purchase as individual components? This flexibility allows you to tailor your chromatography setup to meet your specific needs—whether you're upgrading existing equipment or building a new system from scratch.

Our column accessories are designed to seamlessly integrate with our hardware systems, ensuring optimal performance and ease of use. Need to connect your hardware to high-pressure column packing reservoirs? Our Packing Adapters make the process simple and secure. Plus, we offer a wide range of specialized tools to support your column usage—from installation to maintenance, so you can focus on getting reliable results.

Explore our full selection of components and accessories below to build the perfect system.

Frits

We offer frits manufactured from four different materials: PEEK, stainless steel, UHMWPE, and titanium. All our frits are designed with exceptional uniform porosity and a long filtration life.

Capabilities

  • Outer diameter of the frit matches the tube inner diameter
  • Thickness: 1/32 inch to 1/8 inch
  • Pore rating: Standard offering of 0.5 μm and 2.0 μm with some products available from 0.2 μm up to 10 μm
  • Material: Stainless steel, titanium, PEEK, UHMWPE
  • Function: Retains packing media in the column

Frits for column hardware

Column Tubes

Our high-pressure column tubes include biocompatible PEEK selections as well as seamless stainless steel. Our tubes are manufactured to precise tolerances to ensure product consistency.

Capabilities

  • Internal diameters: 1.0 mm to 10.0 mm
  • Material: Stainless steel or PEEK-lined stainless steel
  • Length: 2 cm to 50 cm
  • Function: Analytical or semi-preparatory scale


Column tubes

End Fittings

Our line of column end fittings are designed to withstand high pressures and be leak-free.

Capabilities

  • Port geometries: Compatible with Valco®, Parker, and Waters® style connections
  • Material: Stainless steel or PEEK to match the tube
  • Function: Secures frit, provides ports to connect 1/16” OD tubing
  • MarvelX / MarvelXACT Assemblies: Not dependent on the port geometry and can be used on a variety of columns without sacrificing performance due to dead space

End fittings for column hardware

 

Guard Columns

Our guard cartridges and holders allow rapid replacement of guard cartridges. Ideal in high-volume production, our cartridges are easy to assemble and pack. Available as stand-alone or integral Modular holders. The integral holders attach directly to the inlet of our Modular Columns without the need for fittings or tubing. Our guard columns extend the life of your analytical pathway by removing particulates and highly adsorptive compounds from the sample. This design offers several advantages over the conventional “stand-alone” holders, including:

Capabilities

  • Reduced dead volume
  • User-friendly, compact design
  • Increased lifetime of analytical columns
  • Simple to assemble and pack

Guard column for column hardware

 

Packing Adapters

Our packing adapters connect our column hardware to high-pressure column packing reservoirs. The adapters are designed for safe, easy removal and replacement of the PEEK sealing ring. Modular packing adapters, IsoBar, and compression columns are available for inner diameters from 2.1 mm to 10.0 mm. Adapters are available for each of our column product families.
Packing adapters for column hardware

 

PEEK ColumnSaver Precolumn Filter

Our ColumnSaver filters offer all the protection of conventional precolumn filters at a third of the cost. With convenient direct connect design, changeover time is measured in seconds; no tools or wrenches are needed. The ColumnSaver PEEK body contains a stainless steel filter element designed for maximum filtration of particulate matter with minimal dead volume or back pressure.


PEEK ColumnSaverâ„¢ Precolumn Filters

IDEX Health & Science’s column hardware products are designed for customers who seek ultimate performance and efficiency. Our column hardware allows you to achieve optimal and repeatable results consistently in your chromatographic separations, and they are ideal for a broad range of Liquid Chromatography (LC) applications, including biopharmaceutical, protein characterization, and proteomics applications. High quality column hardware provides superior separation performance and is a crucial factor in reproducibility of chromatographic data Our ColumnSaver filters offer all the protection of conventional precolumn filters at a third of the cost. With convenient direct connect design, changeover time is measured in seconds; no tools or wrenches are needed. The ColumnSaverPEEK body contains a stainless steel filter element designed for maximum filtration of particulate matter with minimal dead volume or back pressure.

 

Learn more about our column hardware for HPLC and UHPLC applications

View our column hardware brochure