No one wants leaks in their fluidic flow path. Leaks can cause bubbles, low pressure or no pressure and loss of fluid. All of these things can compromise you flow path and results. Leaks are typically caused by fittings—from using improper fittings to chemical capability issues.
Before you see the first drip of mobile phase, your system can warn you that a problem exists.
The most common signs of system leaks are:
While all of these symptoms could also indicate problems unrelated to leaking connections, it is always easiest to start there. Not only are leaking connections usually easy to repair, they are also typically the least expensive repair option.
View our Fittings 101 guide to get more tips and insights on fittings
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Click the link below to open The Column July 2021...
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Wales launched a dedicated photonics network and leadership council, Photonics...
Effective range of “more than 1km” claimed by developers Ministry...
The Schunk Group, a technology company that supplies products made...
Pinning stress on the coronavirus helped couples cope and remain...
Optical fabrication technique enables creation of microdevice that can flexibly...
Southwest Research Institute (SwRI) will create a searchable database of...
A metalens developed by researchers from Cornell University and Samsung...
Series B funding round from Capricorn’s Technology Impact Fund follows...
Group to invest €6M to fund equipment, personnel and R&D...
Research has solved a macabre mystery, and the finding could...
Our resident bacteria help regulate the immune system and response...
Chronic inflammation and immune breakdown appear to be key reasons...
Some studies suggest an impact, particularly for those who are...
New Scale Robotics, a division of New Scale Technologies, has...
Thursday, June 24, 2021 at 12pm EDT |11am CDT |...
I do not believe in classic linear separations anymore—further, I...
Extraction of Oligo therapeutics from biological samples for LC/MS bioanalysis.
The funding will support faculty member Asst. Prof. Kenny Tao...
SPECTARIS industry group expecting a 14% increase in sales by...
University of California, Berkeley develops sensor for faint electric fields...
BRAUNSCHWEIG, Germany — Jörn Stenger of Physikalisch-Technische Bundesanstalt (PTB), Germany’s...
A laser-driven semiconductor switch design can theoretically achieve speeds and...
Fraunhofer ILT, RWTH Aachen develop data center to control and...
California company touts optical phased array technology as game-changer for...
A technique combining 3D printing and immersion in a common...
The American Center for Optics Manufacturing (AMERICOM) has been selected...
To ensure recovery and reproducibility for oligo extraction from tissue,...
Trityl-on methodologies for the analysis of crude synthetic oligonucleotides has...
As synthetic oligonucleotide therapeutics move through the drug-development path, the...
Simple, quick, effective solution for isolating and analyzing therapeutic oligonucleotides...
Clarity QSP provides an alternative trityl-on approach for separating truncated...
Common frequently asked question for oligonucleotides. This includes questions about...
Using the Clarity OTX extraction protocol vendor recommendations, we have...
This technical note discusses 2' cleavage and RNA sample preparation...
Advance your oligonucleotide work, from sample preparation to analysis and...
Europe: Wednesday, June 23, 2021 at 2pm BST | 3pm...
During the development phase of a fluidic system, connecting components...
$5M round supports plan for a 16-satellite constellation providing global...
Deep-learning extrapolates movement from pixels of stationary image.
The universal marker of aging is not always a one-way...
Creators on social media platforms significantly extend the reach of...
Experiments showed that a coating just one molecule thick can...
With the help of a custom-built lattice light-sheet microscope, researchers...
A high-flux and compact cold-atom source with low power consumption...
Tuesday, June 22, 2021 at 10am EDT | 3pm BST...
Even before COVID-19, retailers were turning to vision for better...
New black and white display to replace green image intensifiers;...
Development promises: better high-capacity telecoms; improved potential to find exoplanets;...
The risk of infection increased by up to 30 percent...
Drought and extreme rainfall led to an infestation in the...
Genomic sequencing efforts are limited in developing countries, but scientists...
Researchers use LIGO’s ultra-precise lasers and careful back-action damping to...
Researchers from the University of Bordeaux have found a way...
An international team of researchers has developed a technology that...
Researchers at the University of Rochester’s Institute of Optics have...
Monday, June 21, 2021 at 11am EDT | 8am PDT...
The white paper can be a powerful tool to educate...
Compact, efficient, and highly application specific, embedded vision technology increasingly...
What’s the worst that could happen? -- Read more on...
A noncontact measurement method that uses laser ultrasound so that...
A team at the University of Washington has developed a...
Pandemic highlights for the past two weeks -- Read more...
*Live: Friday, June 18, 2021 at 1pm BST| 8am EDT*...
A round up of this week's coronavirus-related news and countermeasures...
Optical and wireless network test equipment firm’s controlling shareholder wants...
University of Bordeaux models tissue behavior to improve subsequent AO...
Doling out cash rewards and lifting mask mandates could increase...
A prediction system undergoes testing as the U.S. West braces...
Proof-of-concept ultrathin lens can be zoomed and refocused by varying...
A five-year agreement between the University of Maryland, College Park...
Researchers in Russia have increased photoluminescence (PL) in silicon using...
Vision AI software company Neurala launched a European subsidiary, Neruala...
SICK is partnering with Vention, a developer of software for...
University of Tsukuba researchers have tested light-emission hypothesis at molecular...
The international collaboration does not have enough COVID vaccine doses...
Entanglement allows Raman-scattering devices to improve bioimaging without damaging delicate...
Researchers have demonstrated the ability to switch the surface of...
GLASGOW, Scotland — Vector Photonics appointed Jon Orchard principal device...
A method that uses light to manufacture 2D polymers that...
Australian National University-led team demonstrates visible-convertible infrared imaging via non-linear...
Test, measurement, and assurance technology company VIAVI Solutions Inc. has...
*Live: Wednesday, June 16, 2021 at 10am EDT| 7am PDT|...
The company’s ongoing launches of thousands of satellites for global...
A Hokkaido University research team has developed a method to...
Researchers at the University of Waterloo report the first successful...
Field Line of sight Automated Radiance Exposure (FLARE) technique improves...
Undersea cable inspection system developed by partnership of Dive Technologies...
University of Queensland exploits quantum entanglement for uses in Raman...
Analysts at Lux Research suggest that more prosaic applications -...
***Live: Tuesday, June 15, 2021 at 11am EDT | 8am...
GCxGC TOFMS analysis can be overwhelming, but ChromaTOF Tile can...
A fast separation of remdesivir and its active metabolite GS-441524...
Some “gain of function” studies explore how a dangerous pathogen...
Near-infrared light offers a tool for standoff detection and control...
A research team at Texas A&M University is using nanomaterials...
University of Sussex researchers have built and demonstrated a modular...
The “spaceplate” is a new approach to manipulating light that...
International “MEEt” project aiming to adapt novel materials for solar...
David Hagan will serve as dean of the College of...
A method that controls how AI systems create images has...
In this application, serum was cleaned up and compared with...
Testosterone was isolated from plasma using Novum PRO 96-well plates...
An SLE media provides a fast sample prep method. Adding...
An in-well hydrolysis solid-phase extraction (SPE) product is used for...
A quantitative LC–MS/MS method using a room-temperature hydrolysis with an...
Miniaturized LC–MS and SPE method for the reliable and accurate...
In this application, serum was cleaned up and compared with...
Estrone, beta-estradiol, and estriol were derivatized from plasma using Novum...
Miniaturized LC–MS and SPE method for the reliable and accurate...
NASA earth scientist Kerry Meyer and researchers at Harvard University...
A quantum microscope developed at the University of Queensland can...
This application note demonstrates the separation of ten phenolic acids...
This document demonstrates how AMT improves the presentation of the...
The separation of non-steroidal anti-inflammatory drugs 60% less time, with...
This application demonstrates HALO® Biphenyl is an ideal choice for...
Using fast, efficient HALO® Fused-Core® technology columns and manipulating selectivity...
Robotics and automation company Gideon Brothers raised $31 million in...
Friday, June 11, 2021 at 11am EDT | 8am PDT...
This brief demonstrates the extraction and analysis of PFAS compounds...
Unispray ionization is compared to typical electrospray for the analysis...
Read a case study about how an environmental laboratory meets...
This brief demonstrates the extraction and analysis of 25 PFAS...
Workflows for non-targeted analyses for PFAS in wastewater and soil...
Thermo Scientific’s Medical Device (MD) portfolio of liquid chromatography-mass spectrometry...
New production facility in Ohio designed to produce enhanced thin...
After transitioning in 1917, Alan L. Hart helped alter medical...
A new approach to synthesizing quantum dots has significantly increased...
Lumentum Holdings, II-VI, Sumitomo Electric, Nokia, and Ericsson have jointly...
An ultracompact, mid-infrared spectrometer that uses a 10-nm thick, single...
Toshiba’s Cambridge Research Laboratory demonstrated quantum communications over optical fibers...
LZH working within a new research project with Rowiak GmbH...
And the benefits of two four-minute sessions persisted for hours...
Researchers develop an inorganic biomaterial that reacts to near-infrared light...
A novel optical element will one day enable composite lenses...
Thermo Scientific’s Orbitrap Exploris 120 mass spectrometer is designed to...
This application note demonstrates analysis at low levels (ng/L) in...
This application note describes an efficient and reliable method to...
Optical coherence tomography (OCT) is a noninvasive imaging technique that...
Deal includes $300M investment in quantum computing hardware based on...
Platform developed by ICFO combines spectroscopy and ultrasound analysis.
Large gatherings and much more lenient restrictions have allowed the...
An online animal catalogue lets you decode communications and other...
Every two weeks, Scientific American’s senior health editors Tanya Lewis and Josh Fischman catch you...
Researchers from Tokyo University of Science introduced a technique that...
According to recent figures published by deep technology research group...
SAN JOSE, Calif. — Lumentum Holdings appointed Isaac Harris, corporate...
Latest advance from Caltech group demonstrates photoacoustic tomography as route...
Virtual conference running through 11 June 2021; optics.org selects key...
Partners in year-long project include Research Fab Microelectronics Germany and...
Researchers in the Republic of Korea have developed a gold-and-dielectric...
Honeywell Quantum Solutions and Cambridge Quantum Computing will merge, creating...
Wednesday, June 9, 2021 at 1pm EDT | 12pm CDT...
Awaiting the Derek Chauvin verdict, a singer and actor felt intense...
The vast majority of examined incidents were not caused by...
A noninvasive brain imaging technique developed by researchers at ETH...
Using a thin tungsten layer as a restraining, conductive, removable...
Caltech professor Lihong Wang has demonstrated a technology capable of...
SPIE’s annual pitch competition features two photonics-focused tracks, honoring six...
Precision alignment with large-scale wafers to be offered as a...
Dual-band optical stabilization technique cancels out temperature effects that have...
University of Arizona-developed holographic light collector boosts panel efficiency by...
The CW-WDM MSA (Continuous-Wave Wavelength Division Multiplexing Multi-Source Agreement) Group...
*** Tuesday, June 8, 2021 at 11am EDT | 8am...
This application note investigates the use of YMC BioPro SF...
This application note details the use of light scattering detection...
This application note details real-life client data obtained for insulin...
This application note investigates using YMC-Triart C18 for analysis of...
This application note describes the benefits of using YMC-Triart PEEK-lined...
The dial-a-mix method with a quaternary pump HPLC quickly screens...
A noninvasive brain imaging technique developed by researchers at ETH...
Juvenile salmon traveling in the Columbia River near McNary Dam...
Flow cytometry is an incredibly powerful technique that has been...
Circumstantial evidence could point to a mind-blowing solution to an...
Aaron Wheeler, Editor-in-Chief of Lab on a Chip, discusses challenges...
Lab teams leverage optics and photonics to improve the current...
Cutting-edge technologies, new applications, and ideas for the future from...
NASA has selected Brimrose Technology Corporation (BTC) to provide a...
Stimulated scattering in supermode microcavities, such as Raman or Brillouin...
Six startups were named as the winners at the SPIE...
Automated liquid extraction of pesticides from tea that eliminates the...
***Part 1*** ***Airing 1: Monday, June 7, 2021 at 11am...
Demonstrates a rapid method for the identification and quantification of...
In this application note, we present an analytical approach for...
This app note presents a system for characterizing finished coffee...
This application note will demonstrate a fast and easy analytical...
Here we describe a system to extract and concentrate VOCs...
A hyperbolic metamaterial developed at the University of California, San...
A metamaterial absorber developed by researchers from the Korea Institute...
Reducing the column inner diameter results in a reduction in...
Technique that combines quantum dot contrast agent and shortwave infrared...
Researchers at Lawrence Livermore National Laboratory (LLNL) have applied neural...
A laser experiment conducted by scientists at AMOLF (part of...
Researchers from the Institut für Integrierte Produktion Hannover and Laser...
The stochastic theory of chromatography allows one to connect mathematics...
'DAVINCI+' mission selected by NASA will investigate composition of Venus'...
The space agency’s DAVINCI+ and VERITAS missions could boost planetary...
Jennifer Cable has been named president of photonics equipment manufacturer...
Diffuse optical localization imaging allows microangiography without invasive surgery.
A detailed analysis suggests that COVID deaths and other pandemic-related...
An oil-filled optical cavity exhibits broadband stochastic resonance, and points...
An “artificial retina” developed at the University of Sydney may...
A team of scientists and engineers from Katholieke Universiteit (KU)...
TORONTO — Synaptive Medical appointed Mark Hanrahan CFO. Hanrahan joins...
Following rising demand from semiconductor sector, photonics group acquires new...
Huazhong University project applies near-IR to nanoparticles and algae for...
...as Netherlands partners sign up for new Photonic Integration Technology...
This application note exploits the highly retentive but universal nature...
The timsTOF Pro 2 is designed for robust, unbiased, deep...
The timsTOF SCP from Bruker is designed as a dedicated...
Catching bison is a hassle. It’s also expensive. For most,...
UC San Diego’s method coats microscope slide with metamaterial composed...
“QualLa” project is partnership of LZH and Institute for Integrated...
Dynetics wins NASA contract to produce laser air monitoring spectrometer...
Dresden-based developer of tiny organic semiconductor sensors looks to mass-market...
Applied science and information technology company Dynetics Inc. was awarded...
Optoelectrowetting (OEW) is a digital optofluidic technology based on the...
McGill University researchers set out to uncover the secrets of...
*Tuesday, June 1, 2021 at 12:30pm BST| 1:30pm CEST| 7:30am...
Click the link below to open The Column June 2021...
Click the link below to open The Column June 2021...
Click the link below to open The Column June 2021...
Extract pesticides from cannabis flower and edibles with one simple...
In recent articles, we reviewed the basic concepts of extracolumn...
This exploration into commercially available light scattering detection systems for...
We present the main analytical techniques for performing functional characterization...
This is the first article in a four-part series exploring...
Solid adsorbent gas chromatography (GC) columns, such as porous layer...
The incorporation of a post-column reaction using a 3D-printed, two-stage...
Computer-enabled technology approaches can mitigate the impact of aging instruments...
Per- and polyfluoroalkyl substances (PFAS) in surface water have become...
Modern ion mobility–mass spectrometry (IM–MS) is a key separation technology...
Funding for new FMCW lidar developer agreed with participation of...
A laser-based cutting technique is able to reduce hazardous waste...
Researchers at Centre Spatial de Liege (CSL) of the University...
For One Customer, this Resulted in Aspirating Patient Samples More...
Standard treatments such as steroids, as well as illnesses such...
Just one of the seven Millennium Prize Problems named 21...
Snap Inc., the maker of the Snapchat app, will acquire...
A combination of OCT, adaptive optics, and neural networks has...
CEA-Leti has unveiled an autonomous imager technology that is able...
Machine vision company SiLC Technologies raised $17 million in a...
For new approaches to biometric access control, 3D locks, and...
A combination of OCT, adaptive optics, and neural networks has...
US startup says its FMCW imaging chip will enable machines,...
Upconversion nanoparticles, coupled with a photosynthetic bacterium, could enable a...
*** Asia Pacific: Thursday, May 27, 2021 at 9am CST...
Investment to drive Canadian startup’s progress toward a quantum computing...
Treatment combining gene therapy and light-stimulating goggles reportedly enables partial...
Robert Bauer, chairman of SICK AG’s executive board, will leave...
Carnegie Mellon University (CMU) received a $75 million grant from...
Researchers from the University of Colorado Boulder have developed optical...
A light-harvesting nanomaterial inspired by the hierarchically structured biominerals in...
Lynred, the developer of IR detectors that last month was...
French high-tech firm acquires compatriots Kylia and Muquans as it...
Imec clinical study identifies signs of plaque accumulation in the...
The “slow-slip” event preceded a devastating 1861 quake, at least...
A spectroscopy technique has enabled the study of nanolevel imperfections...
Researchers at Brussels Photonics (B-PHOT), Vrije Universiteit Brussel, Belgium, developed...
...while Stuttgart researchers 3D-print complex micro-optics to enable improved imaging...
The “slow slip” event preceded a devastating 1861 quake of...
Leveraging nitrogen–vacancy centers in diamond may enable approach that combines...
Separation science is an intriguing and challenging (yes, let’s admit...
Eye-tracking technology company Smart Eye and emotion-monitoring software company Affectiva...
The CELLINK Group, a bioconvergence company focused on the application...
Light-sensing proteins called rhodopsins are used in optogenetics to control...
The Indian Institute of Technology Delhi (IIT Delhi) will establish...
Adding antibodies to photodynamic therapies can bolster their efficacy, according...
µWAI (Micro-WAY) sensor is designed for smart phones, smart appliances;...
Swedish bio-printing pioneer says it will gain a ‘leg up’...
UK-based maker of augmented reality waveguides based on diffraction gratings...
University of Vienna project develops optical coatings with record-low losses...
A study counts blood cells and footsteps to predict a...
Streamline beverage analysis with ion chromatography. Learn how to determine...
This application note investigates the differences between packaging of normal...
A study counts blood cells and footsteps to predict a...
Adding antibodies to photodynamic therapies can bolster their efficacy, according...
Light-sensing proteins called rhodopsins are used in optogenetics to control...
A light sensor developed by the University of Texas at...
The Dark Energy Spectroscopic Instrument (DESI) has begun its five-year...
Researchers from the University of Stuttgart used a 3D-printing process...
***Live: Monday, May 24, 2021 at 11am EDT | 8am...
Aim is to provide “lotus effects” and other laser-created microstructures...
With newly-developed approach, up to 95% less radioactively contaminated secondary...
A new nanomaterial mixture lets surfaces release more heat than...
Collaborators from industry and academia have demonstrated high-performance laser mirrors...
Photonics company iXblue has acquired optical components and instruments company...
A hybrid camera system built by researchers at Shibaura Institute...
***Thursday and Friday May 13-14 | May 20-21, 2021*** In...
Mary Ellen McNally, PhD, is a Global R&D Fellow at...
Waters Corporation founder James L. Waters, a legendary inventor and...
Collaborators from industry and academia have demonstrated high-performance laser mirrors...
Researchers at Shibaura Institute of Technology develop hybrid camera enabling...
There may be realistic ways to create cosmic bridges predicted...
Through a wireless implant that triggers neurons with light, scientists...
Researchers at Raytheon BBN Technologies developed a method of single-photon...
A collaboration between scientists from the University of New Mexico,...
Researchers at the Fralin Biomedical Research Institute at Virginia Tech...
Semtech providing laser driver and transimpedance amplifier elements to support...
Zebra Technologies has entered the machine vision market with its...
The 30 mg Microlute® CP Strong Cation Exchange (SCX) 96...
This note demonstrates the determination of PAH4 inedible oils with...
This application note presents the rapid analysis and quantification of...
Researchers at the Fralin Biomedical Research Institute at Virginia Tech...
Sales up at fiber-optic sensing specialist; OptaSense subsidiary inks deal...
COVID deaths are leaving millions bereaved. For some, the intense...
Samuel Ignacio Zapata-Valencia has been awarded the 2021 Teddi C....
Researchers at the University of Maryland have shown that photons...
BAD OLDESLOE, Germany — Automation Technology (AT) named Guido Deutz...
An integrated approach that uses a single-photon emitter embedded in...
A possible key to developing reliable navigation in autonomous vehicles...
Continued strength in lithography and a rebound in medical and...
After pandemic hit last year’s sales, recovery is mainly due...
Recent findings have implications for the design of prostheses. Care...
Researchers believe that laser-based system for creating and annihilating quasiparticles...
This application demonstrates the efficiency, throughput, and reliability of a...
Cannabinoids have similar molecular structures, making purification a challenging step....
COVID deaths are leaving millions bereaved. For some, the intense...
Samuel Ignacio Zapata-Valencia has been awarded the 2021 Teddi C....
PRESS RELEASE FOR IMMEDIATE RELEASE For further information, please contact:...
Via a new Royal Society Industry Fellowship at the Zepler...
FDA Breakthrough Device status allows priority review of clinical and...
Researchers at MIT have developed a method to rapidly change...
A spectroscopy technique developed at the University of California, Davis...
Technique used at Tampa General Hospital to help place three...
Japanese company to expand operations and develop new molecular diagnostics...
University of Cambridge takes detailed measurements of ice properties on...
New research shows how much warming is costing society by...
New research shows how much warming is costing society by...
A spectroscopy technique developed at the University of California, Davis...
Seafood is often falsely labeled, but a handheld device can...
A University of Nottingham research team has developed a phonon...
NASA engineers have rendered the the Mars helicopter Ingenuity’s third...
This summer, NASA will launch its Laser Communications Relay Demonstration...
New type of Josephson junction developed by ICFO, MIT, et...
Automation Technology (AT) named Guido Deutz business development manager. Deutz...
This yearly report on new products introduced in the preceding...
Our annual review of new liquid chromatography columns and accessories,...
A review of the history and fundamentals for determining and...
This instalment focuses on basic concepts in extracolumn dispersion (ECD)...
Second only to the U.S. in a fully successful Mars...
UK-based partnership of Microlink Devices, Wideblue and CSA Catapult to...
New Institute of Electronic-Photonic Integrated Circuits for Aerospace (EPICA) to...
As Aedes aegypti mosquitoes increase their range because of warming...
A microLED developed at KAUST is able to efficiently emit...
A technique developed at the University of Rochester “flips” the...
Using GC×GC–TOF-MS and tandem ionisation to identify trace additives in...
Showing how the comprehensive data acquired using GC×GC–TOF-MS with tandem...
Learn how your lab can benefit from smarter GC‒MS instruments...
The use of headspace sorptive extraction with GC×GC–TOF-MS to compare...
TI data improves discovery workflows by reducing the frequency of...
Using TD–GC×GC–TOF-MS for profiling of biomarkers in breath and data...
Technical note describing the use of tandem ionisation for BenchTOF2...
Researchers at Gothenburg and KTH universities, both based in Sweden,...
Stock price tumbles after photonics company defers $15M revenues in...
The agency’s latest guidelines provide an incentive for people to...
