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A team of researchers from the U.S. and China, led by Robert Alfano from City University of New York, has used visible resonance Raman (VRR) spectroscopy to identify and grade gliomas, a common tumor of the central nervous system. The researchers used in situ spectral biomarkers to identify the tissue from the interface between brain cancer and normal tissue and to evaluate glioma grades. Analyses of the VRR spectra revealed that the major molecular biomarkers are involved in metabolic processes in human brain tissues and can be used to create an optical molecular pathology method.
The VRR approach to identifying and grading tumors is a continuation of the Alfano group’s work in the area of optical biopsy, a field that the…READ MORE