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First reported in 1991 by Huang and colleagues1, OCT has become an important imaging tool for ophthalmology following innovations over the past three decades. OCT noninvasively provides 3D in vivo optical biopsy with microscopic resolution in the eye at a depth range up to the choroid2. Besides 3D anatomical imaging, OCT can also provide functional information. The most notable functional extension is OCT angiography (OCTA), which can map the microvasculature in the eye without contrast agent and is being investigated in clinical ophthalmology.
A multicolored retinal blood oxygen saturation map overlaid on a VIS-OCT angiogram. Adapted from Reference 5.
OCTA opens up a new window on better managing a wide variety of blinding…