The LCGC Blog: A New View of Reversed-Phase HPLC Selectivity - IDEX Health & ScienceIDEX Health & Science

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    The LCGC Blog: A New View of Reversed-Phase HPLC Selectivity

    Article obtained from LCGC Liquid Chromatography (LC/HPLC) RSS Feed.

    Over the 17 years since the original Hydrophobic Subtraction Model for HPLC selectivity was published, those who curate the model have collected a huge amount of data as new HPLC stationary phases have been added. Analysis of this new data on almost 600 stationary phases has allowed us to update or adjust several of the stationary phase–analyte interaction terms within the model as well as adding one entirely new term to better describe the dipolar interactions with more modern stationary phases such as the pentafluoro phenyl-type phases.

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    Apr, 05 2021 |

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