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Going with the flow is rarely a bad thing. Unless you’re talking about the notorious pathogen Pseudomonas. The bacterium is almost always surrounded by flowing water, and researchers are using part of that phenomenon to measure the flow of cells within the body.
They discovered that the pathogen detects flow and changes its behavior accordingly by activating genes that the Princeton-based researchers have dubbed “fro,” for “flow regulated operon.” They then used gene cloning to engineer a connection between fro and a yellow fluorescent protein that causes the bacterium to glow, said Joseph Sanfilippo, a lead author on the paper.
A team of Princeton University biologists and engineers led by Zemer…READ MORE