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An endoscope that combines photoacoustic and fluorescence imaging and that is about as thick as a human hair could one day provide insight into the brain by enabling the simultaneous measurement of blood dynamics and neuronal activity. The researchers responsible for developing the device fabricated a prototype microendoscope that measured just 250 × 125 µm2, and used it to image fluorescent beads and blood cells using both imaging modalities. They successfully detected multiple 1-µm fluorescent beads and individual 6-µm red blood cells.
“Combining these imaging modalities could improve our understanding of the brain’s structure and behavior in specific conditions such as after treatment with a…READ MORE