Reflection Matrix Microscopy Could Expedite Neuroscience Research - IDEX Health & ScienceIDEX Health & Science


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    Reflection Matrix Microscopy Could Expedite Neuroscience Research

    Article obtained from BioPhotonics RSS Feed.

    A South Korean research team has developed an optical microscope capable of maintaining spatial resolution and acquiring a microscopic “map” of neural network activity in brain tissue as it images through the width of an intact mouse skull. The device pairs hardware components with computational adaptive optics (AO); the latter was initially conceptualized to correct optical aberrations in ground-based astronomy.

    Testing showed the ability of the microscope to capture two-photon fluorescence images of a dendritic spine of a neuron behind a mouse skull with a spatial resolution near the diffraction limit. The achievement, team members report, makes it possible to examine a mouse brain in its native states.

    To image a…

    Dec, 04 2020 |

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