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Scientists from Stevens Institute of Technology and Baylor College of Medicine used 4D optical coherence tomography (OCT) to study the pumping mechanism underlying the developing mammalian heart. 4D OCT allowed them to investigate the functional relation between blood flow and heart wall dynamics within different regions of the embryonic heart at a level of detail not currently accessible by other methods. 4D OCT could potentially enable scientists to assess cardiac pumping over embryonic development as the heart tube remodels, which could reveal functional changes during early cardiogenesis that lead to congenital heart defects.
The researchers used 4D OCT to obtain structural and Doppler hemodynamic imaging of the beating heart in…READ MORE