Disclaimer:

    The views, information, or opinions expressed in the Industry News RSS feed belong solely to the author and do not necessarily represent those of IDEX Health & Science and its employees.

    New Molecule Marker Enables ‘Unprecedented’ Study of Mitochondria

    Article obtained from Photonics RSS Feed.

    A team at Nagoya University’s Institute of Transformative Bio-Molecules has developed a marker molecule that bypasses the problem of photobleaching in STED microscopy. It’s allowing an unprecedented view of live mitochondria, which could help researchers better understand, diagnose, and potentially cure human mitochondrial disease.

    The new marker molecule — MitoPB Yellow — is absorbed by the inner membrane of mitochondria, which includes the cristae (fold-like structures), and has demonstrated a long lifetime under a STED beam.

    According to the researchers, existing marker molecules succumb to photobleaching when they degrade under intense STED beams and stop fluorescing, making it nearly impossible to…

    READ MORE
    Oct, 22 2019 |

    IDEX Health & Science is the global authority in fluidics and optics, bringing to life advanced optofluidic technologies with our products, people, and engineering expertise. Intelligent solutions for life.