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A fluorescence microscope being developed by imec researchers will be able to achieve high throughput and high resolution, without a lens component. The technology could significantly speed up next-generation DNA sequencing and cellular research, as well as enable studies on larger scales.
Part of the trouble that researchers face with ordinary fluorescence microscopes, said Niels Verellen, principal scientist at imec, stems from certain limitations of lenses. As magnification increases, throughput — or field of view — decreases.
The light field’s interference patterns can be precisely controlled to form illumination spots. Courtesy of Niels Verellen/imec.
“We are looking for a way to do fluorescence…