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A Massachusetts General Hospital-based research team has introduced an intravascular laser speckle imaging (ILSI) technique that showed the ability to identify the distinct mechanical features of plaques that are most apt to rupture under the physiological conditions of cardiac motion, blood flow, and breathing. The rupture of unstable coronary plaques can cause arterial blockage, leading to heart attack.
The research charts a course for scientists to obtain the visual information necessary to deliver pharmacological insights that could aid in the development of treatments and preventative approaches for the prevention of heart attacks.
The researchers deployed a small-diameter intravascular catheter device that delivered light…
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