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Researchers at the University of Colorado Anschutz Medical Campus have found that intense light amplifies a specific gene — Period 2 (PER2) — that makes the metabolism of mice and humans more oxygen-efficient. This amplification could offer protection against injury to the heart muscle if the light therapy were given before high-risk cardiac and noncardiac surgery.
The scientists sought to develop a cardio-protective strategy using light to target and manipulate the function of the PER2 gene, which is expressed in a circadian pattern in the part of the brain that controls circadian rhythms. They investigated intense light exposure protocols in mice and found that housing mice under intense light conditions (10,000 lux,…READ MORE