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By increasing the uniformity of light dispersed across the field of view, a team of biophysicists from the Laboratory of Experimental Biophysics (LEB) at École Polytechnique Federale de Lausanne has successfully increased the size of images it can capture using a superresolution fluorescence microscope.
The biophysicists relied on the enhanced technology to capture detailed images of the twists found within centrioles. Cells contain a pair of centrioles, the organelle responsible for segregating chromosomes during cell division.
Through the design of its high-throughput superresolution microscope that uses light to probe specimens, the team was able to observe centrioles while they were still inside living cells.