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A noninvasive brain imaging technique developed by researchers at ETH Zurich and the University of Zurich works in the near-infrared (NIR) spectrum to enable superresolution deep-tissue fluorescence microscopy at four times the depth limit imposed by light diffusion. According to the researchers, the technique, called diffuse optical localization imaging (DOLI), operates in a resolution-depth regime previously inaccessible with optical methods.
DOLI could allow scientists to study neuronal processes at the level of single cells and capillaries across the entire living brain without needing to use highly invasive surgical methods.
DOLI uses a combination of individual techniques to enable noninvasive deep brain imaging at high…READ MORE