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Researchers from Tsinghua University have developed a way to image multiple areas of the brain at the same time, both on the brain’s surface and deep inside the brain. Since brain processes often span multiple regions of the brain, researchers say the new approach could lead to a more complete understanding of how the brain works in health and disease.
To allow simultaneous imaging of multiple areas and depths in the brain, the researchers implanted glass windows in the heads of living mice. They accomplished this by removing part of the skull and implanting two separate windows into the brain. The first window was a glass plug 2 mm wide and 0.9 mm tall. The second window was a microprism in the shape of a 1-mm cube.