Breaking the Rules: Two- and Three-Dimensional Chromatography with Four Dimensions of Mass Spectrometry - IDEX Health & ScienceIDEX Health & Science

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    Breaking the Rules: Two- and Three-Dimensional Chromatography with Four Dimensions of Mass Spectrometry

    Article obtained from LCGC Liquid Chromatography (LC/HPLC) RSS Feed.

    Two-dimensional liquid chromatography (2D-LC) allows much greater resolution of peaks than is possible in a classical single dimensional separation. For the next development in separations, we employed 2D-LC in two highly orthogonal dimensions of separation with four mass spectrometers for detection, with parallel detection in each dimension. We have further broken ground by using three dimensions of separation with four mass spectrometers, using two parallel second dimensions.

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    May, 01 2021 |

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