Avoiding Depurination During Trityl-on Purification v2 - IDEX Health & ScienceIDEX Health & Science


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    Avoiding Depurination During Trityl-on Purification v2

    Article obtained from LCGC Liquid Chromatography (LC/HPLC) RSS Feed.

    Trityl-on methodologies for the analysis of crude synthetic oligonucleotides has many benefits however depurination during trityl-on methodologies can lead to nucleic acid damage. This technical note explores a new trityl-on procedure that minimizes the risk of depurination.

    Jun, 23 2021 |

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