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    Aggregate and Fragment Analysis in Therapeutic Monoclonal Antibodies Using On-Line Size-Exclusion Chromatography with Native Mass Spectrometry

    Article obtained from LCGC Mass Spectrometry RSS Feed.

    Aggregates and fragments are common product-related impurities in biopharmaceuticals that have impact on efficacy, safety, and stability. Identification of these low-level impurities may involve labor-intensive chromatographic fraction collection and follow-up experiments. In addition, a signi

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    May, 01 2020 |

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