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Flow Cytometry Technique Shows Promise for Early Cancer Diagnosis

Sep 8, 2022, 03:00 AM by System

A digital droplet microfluidic flow cytometry technique could enable earlier recognition of tumor development and progress, by aiding in the detection of multiple microRNAs (miRNAs) in single circulating tumor cells (CTCs). Tumor-associated miRNAs within CTCs are considered biomarkers for tumor growth.

According to the research team behind the technique, current CTC detection strategies that are based on surface epithelial markers exhibit low specificity in distinguishing between CTCs and epithelial cells in hematopoietic cell populations. So far, it has been challenging for scientists to devise a way to perform in situ analysis of multiple miRNAs of single living CTCs.

In the recent work, the team led by professor Chen Yan...
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