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King Abdullah University of Science and Technology (KAUST) researchers developed an ultrathin stimulated Raman scattering (SRS) lens that will simplify and improve the quality of molecular-level microscopic analysis by alleviating a prevalent drawback of SRS microscopy. The optical device, which resembles a miniaturized lighthouse lens, combats the likelihood that intense interactions between laser pulses and samples under observation will generate cross-phase modulation — a background signal that prevents the detection system’s ability to image without interference.
Whereas many bioimaging techniques require fluorescent dyes to be added to cell targets prior to observation, SRS microscopy avoids the cumbersome labeling…READ MORE